منابع مشابه
Spatial Manipulation with Microfluidics
Biochemical gradients convey information through space, time, and concentration, and are ultimately capable of spatially resolving distinct cellular phenotypes, such as differentiation, proliferation, and migration. How these gradients develop, evolve, and function during development, homeostasis, and various disease states is a subject of intense interest across a variety of disciplines. Micro...
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Electrowetting-on-dielectric (EWD) droplet actuation has been used widely in handling liquid in small quantities in many biological applications (Fair et al. 2007; Miller and Wheeler 2009; Boles et al. 2011; Welch et al. 2011). The droplet is manipulated by applying voltage to EWD electrodes buried beneath an insulator (Fair et al. 2007; Boles et al. 2011; Welch et al. 2011). Many droplet funct...
متن کاملMicrofluidics-Based Cell Manipulation and Analysis
Micro total analysis system, likewise named “lab on a chip”, integrates sequentially analytical processes such as pre-treatment, separation, and detection of samples in a single microfluidic device. Microfluidics-based analysis systems have witnessed significant developments in applications of many research fields (e.g., chemistry, physics, and medicine) over the last two decades, becoming incr...
متن کاملHybrid opto-electric manipulation in microfluidics-opportunities and challenges.
Hybrid opto-electric manipulation in microfluidics/nanofluidics refers to a set of methodologies employing optical modulation of electrokinetic schemes to achieve particle or fluid manipulation at the micro- and nano-scale. Over the last decade, a set of methodologies, which differ in their modulation strategy and/or the length scale of operation, have emerged. These techniques offer new opport...
متن کاملManipulation of Suspended Single Cells by Microfluidics and Optical Tweezers.
Chondrocytes and osteoblasts experience multiple stresses in vivo. The optimum mechanical conditions for cell health are not fully understood. This paper describes the optical and microfluidic mechanical manipulation of single suspended cells enabled by the μPIVOT, an integrated micron resolution particle image velocimeter (μPIV) and dual optical tweezers instrument (OT). In this study, we exam...
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ژورنال
عنوان ژورنال: Frontiers in Bioengineering and Biotechnology
سال: 2015
ISSN: 2296-4185
DOI: 10.3389/fbioe.2015.00039